Abstract

     The present study was designed to evaluate biochemical   constituents of the sera of patients with renal calculi. Also, this research is designed to evaluate calcium, oxalate and total protein in 24 hour urine for 22 patients compared with 14 other healthy people as control group. The current study deals with the age, sex and smoking effect on the composition of renal calculi and considered to study.

   The protocol of the research consisted of qualitative analysis of   renal calculi. Twenty-eight calculi were obtained from (8) females and   (20) males afflicated with Urolithiasis. Their ages ranged from (7-60) years.         Biochemical analysis of sera was carried out by using quantity method analysis and the result was designed to calculate the concentration of Glucose,urea,Creatinine, uric acid, calcium, phosphorus, total protien,acid phosphatase and alkaline phosphatase levels. Showing of resulting data demonstrated that significant P<(0.05) differences of serum glucose concentration between males and females.                                                          

   The study explained of the effect on biochemical constituent were pointed out that increased significant (p<0.05) postive correlation with age for serum glucose, urea, Creatinine ,uric acid, calcium. while appeared decreased significantly (p>0.05) negative correlation with age for serum phosphorus, Acid phosphatase and Alkaline phosphatase .                                      

   The peak age of patient with renal calculi was found to be in (7-48) years. The effect of smoking factors not to have any changes on the constituents of the study.

Data of urinalysis of 24 hours were increased for concentration calcium, oxalate and total protein of patient when compared with healthy people as control group.                                                                                    

Qualitative assay of renal stone appeared higher percentages uric acid , calcium,oxalate,phosphours and ammonium   in calculi of males when compared with that of females.

     This study recommendations: Establishment of ideological stone therapy in A L-furat AL-awsat, public educatin,Qualitative analysis of kidney stone ,Using technique (FTIR) ,Control of chronic disease, for example Diabetes mellitus ,Family history ,hypertension, A history of gout,hyperparathyrodisum and Chronic metabolic acidosis. More studies about relation between smoker and renal calculi .